top of page

Crossbow Therapeutics is looking for a full-time

Associate Director/

Crossbow Therapeutics, Inc., is a biotechnology company determined to improve the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. The company’s T-Bolt™ therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell targets. Crossbow’s efficient and selective approach is designed to target the entire universe of cancer proteins, dramatically expanding the potential of antibody therapy to address many types of cancer.

Join us on our bold quest to broaden the benefits of immunotherapy and improve the lives of people living with cancer. For more information, visit us at

About The Opportunity 

Crossbow is seeking an Associate Director of Translational Medicine specializing in
immuno-oncology to join our dynamic team. In this role, you will leverage your experience
in translational medicine to help advance and guide the development of our innovative
therapies for patients living with cancer.

Key Responsibilities: 

  • Develops and leads translational strategy and efforts for individual programs to help  advance Crossbow’s therapeutic pipeline towards the clinic.

  • Provides oversight of the development, validation, and execution of clinical  biomarker and PK/PD assays with external CROs and actively manages vendor  relationships.

  • Drives clinical biomarker and PK/PD sample testing and data analysis in close  collaboration with clinical and development operations line functions.

  • Serves as the translational medicine lead representative to cross-functional  program teams and helps to drive integrated program development plans.

  • Leads external collaborations and sponsored research agreements that enable  translational efforts to help inform and advance our therapeutic pipeline.

  • Prepares and reviews translational medicine sections of IBs, INDs, abstracts,  manuscripts, and technical reports.

  • Leads and supports internal biomarker assay development experiments and efforts at the bench to enable patient stratification, pharmacodynamic assessment, and  clinical response prediction.

  • Provides translational scientific and strategic input into novel target identification.

  • Understands project timelines and deliverables, and plans/coordinates project  work accordingly with departmental, functional, and other stakeholders.

Preferred qualifications and past experience: 

  • Ph.D. in Immunology, Molecular Biology, Cancer Biology, or other scientifically
    related field

  • 7-10 years post graduate with significant translational science research, clinical
    biomarker assay development, and clinical trial industry experience is required.

  • A strong background in immuno-oncology with experience in large molecule
    antibody development is preferred.

  • Experience across a broad number of analytical platforms including multiparameter
    FACS, multiplex immunoassay platforms, and bioanalytical assay development is
    highly desirable.

  • Strong team player with the ability to work in cross-functional teams.

  • Excellent interpersonal, verbal, and written communication skills.

  • While some flexibility may be offered, the primary expectation is for on site work at
    our Cambridge location.


To apply for this role: Send your resume directly to

Location: This position is full-time, on site at Crossbow’s Cambridge, MA office. Crossbow Therapeutics is located at 1030 Massachusetts Ave. Suite 210, Cambridge, MA.

To all agencies: All resumes submitted by search firms/employment agencies at Crossbow via email, the internet, or in any form and/or method will be deemed the sole property of Crossbow Therapeutics and no fee will be paid by Crossbow, unless such search firms/employment agencies were engaged by Crossbow for this position and a valid agreement is in place.

A note about recruitment scams: Please be aware of potential recruitment scams, which can appear like legitimate work opportunities where the scammer pretends to work at Crossbow Therapeutics. To help protect yourself from those types of scams, please know that

  • Crossbow will never ask for money or fees at any point during the interview process - if you are being asked to send money as part of your interaction, do not send money;

  • Crossbow never asks applicants to communicate through Telegram or Skype - if you are being asked to download Telegram or Skype for a job interview, do not download;

  • Crossbow employees will only email you from an official email account.

bottom of page