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Crossbow Therapeutics is looking for a

Senior Scientist/ Principal Scientist, Biology 

Crossbow Therapeutics, Inc., is a biotechnology company determined to improve the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. The company’s T-Bolt™ therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell targets. Crossbow’s efficient and selective approach is designed to target the entire universe of cancer proteins, dramatically expanding the potential of antibody therapy to address many types of cancer.

Join us on our bold quest to broaden the benefits of immunotherapy and improve the lives of people living with cancer. For more information, visit us at

About The Opportunity 

This is an opportunity to be part of an exciting and growing Biology team. The level of the position will be commensurate with the candidate’s education and industry experience.

Key Responsibilities: 

  • Lead one or more discovery programs.

  • Independently work to generate, critically analyze and interpret data with scientific rigor and an open mind.

  • Lead the design and execution of immune cell-based experiments.

  • Perform multiparameter flow cytometry-based experiments.

  • Work collaboratively with scientists and research associates within and across teams to accomplish program goals.

  • Thorough documentation of experiments and communication of results with scientific team members and stakeholders. 

  • Presentation of program strategy and progress to research leadership team, as well for external scientific meetings.

  • Contribute to maintaining a creative and safe laboratory environment.

Preferred qualifications and past experience: 

  • Ph.D. in Immunology or Cancer Biology with more than 3+ years of experience in either an academic or industrial setting. B.S./M.S. with more than 8+ years of experience in Immunology, preferably in Immuno-oncology.

  • The ideal candidate would have strong background in Immunology with understanding how cytotoxic T cell recognize and eliminate target cells.

  • Demonstrated experience with flow cytometry, including FlowJo data analysis. 

  • Experience with techniques related to T cell immunology and tumor immunotherapy, such as T cell dependent cellular cytotoxicity assays.

  • Ability to thrive in a highly collaborative fast-moving small biotech environment.

  • Pro-active problem solver, strong interpersonal skills, highly collaborative, and outstanding communication skills.

  • Ability to present and explain research to a wide variety of audiences. 

  • A creative, flexible and self-motivated individual.

  • The candidate must have a passion for conducting experiments and being part of a strong lab team.

  • Management experience is a plus and may position the candidate to build and lead a team of scientists as the company grows.


To apply for this role: Send your resume directly to

Location: This position is full-time, on site at Crossbow’s Cambridge, MA office. Crossbow Therapeutics is located at 1030 Massachusetts Ave. Suite 210, Cambridge, Massachusetts.

To all agencies: All resumes submitted by search firms/employment agencies at Crossbow via email, the internet, or in any form and/or method will be deemed the sole property of Crossbow Therapeutics and no fee will be paid by Crossbow, unless such search firms/employment agencies were engaged by Crossbow for this position and a valid agreement is in place.

A note about recruitment scams: Please be aware of potential recruitment scams, which can appear like legitimate work opportunities where the scammer pretends to work at Crossbow Therapeutics. To help protect yourself from those types of scams, please know that

  • Crossbow will never ask for money or fees at any point during the interview process - if you are being asked to send money as part of your interaction, do not send money;

  • Crossbow never asks applicants to communicate through Telegram or Skype - if you are being asked to download Telegram or Skype for a job interview, do not download;

  • Crossbow employees will only email you from an official email account.

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